Practicing Evidence-Based Medicine is Essentially a

Five Step Process

 

1. Defining the question using the PICO format:

P=Problem
I=Intervention or Indicator
C=Comparison or Complication
O=Outcome

2. Deciding the kind of question:
Usually either diagnosis and screening, prognosis, therapy, or exposure and harm

3. Searching for the answer by using optimal resources for that type of question

4. Critically appraising the findings to determine what are the results, if they are valid, and if the results will help in your work

5. Determining if the findings are both valid and important, and how they can be integrated into practice in accordance with clinical judgment and patient beliefs

Systematic Reviews are written by reviewers who use explicit and rigorous methods to identify, critically appraise, and synthesize relevant studies from the published medical research. How Do I Find a Systematic Review?

  • Search MEDLINE in PubMed for your question. Under Clinical Queries, there is an option for “Find Systematic Reviews”. This search finds citations for systematic reviews, meta-analyses, reviews of clinical trials, evidence-based medicine, consensus development conferences, and guidelines. Be aware that this is NOT the same as searching the Cochrane Database of Systematic Reviews directly.

PubMed - in the Limits section under Publication Types, use the Review option.

Meta-Analysis is a systematic review that uses quantitative methods to summarize research results preferably using randomized controlled trials.

Search MEDLINE in PubMed for your question. Under Clinical Queries, there is an option for “Find Systematic Reviews”. This search finds citations for systematic reviews, meta-analyses, reviews of clinical trials, evidence-based medicine, consensus development conferences, and guidelines. Be aware that this is NOT the same as searching the Cochrane Database of Systematic Reviews directly.
Search "Cochrane Database of Systematic Reviews" on the Ovid system. Some of these reviews are also meta-analysis.

PubMed - in the Limits section under Publication Types, use the Meta-Analysis limit.

 

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