I work with Dr. Danny Bluestein in bio-fluid lab located in HSC (Health Science Center) in Stony Brook.  My research is focused on numerical simulations of blood flow through mechanical heart valves and stenossed blood vessels looking at platelet activation due to flow stresses.  We use CFD to solve the flow problem and some post processing techniques to calculate the platelet damage accumulation.  The CFD (computational fluid dynamics) code we use in the lab is finite element based code called FIDAP (Fluent Inc.).  

 

Publications

·        Ricotta, J.J., J. Pagan, M. Xenos, Y. Alemu, S. Einav, and D. Bluestein, “Cardiovascular disease management: the need for better diagnostics.” Med Biol Eng Comput, 2008. 46(11): p. 1059-68.

·        Rissland, P., Y. Alemu, S. Einav, J. Ricotta, and D. Bluestein, “Abdominal Aortic Aneurysm Risk of Rupture: Patient-Specific FSI Simulations Using Anisotropic Model.” Journal of Biomechanical Engineering, 2009. 131(3): p. 031001.

·        Bluestein, D., Y. Alemu, I. Avrahami, M. Gharib, K. Dumont, J.J. Ricotta, and S. Einav, “Influence of microcalcifications on vulnerable plaque mechanics using FSI modeling.” Journal of Biomechanics, 2008. 41(5): p. 1111-1118.

·        Alemu, Y. and D. Bluestein, “Flow-induced platelet activation and damage accumulation in a mechanical heart valve: numerical studies.” Artificial Organs, 2007. 31(9): p. 677-88.

·        Yin, W., Y. Alemu, K. Affeld, J. Jesty, and D. Bluestein, “Flow-induced platelet activation in bileaflet and monoleaflet mechanical heart valves.” Annals of Biomedical Engineering, 2004. 32(8): p. 1058-66.

·        Raz, S., S. Einav, Y. Alemu, and D. Bluestein, “DPIV prediction of flow induced platelet activation-comparison to numerical predictions.” Annals of Biomedical Engineering, 2007. 35(4): p. 493-504.

 

Some pictures

 

Velocity near valve region of a 3D St. Jude mechanical heart valve

 

 

A 3D transient representation of arterial stenosis model (input velocity vs. time curve shown)